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Paper accepted at Cell Reports!!

16/8/2017

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Update August 25th.
Our paper has now been officially accepted in Cell Reports!!

​
Brent has co-authored a paper that has been accepted in principle for publication in Cell Reports!

Our results define how the lin-14 heterochronic gene (one responsible for controlling the timing of developmental processes) controls axonal degeneration in C. elegans.  We found that interactions between an axon and it's surrounding environment is critical for preserving axonal structure throughout life.  Interestingly, the function of the LIN-14 transcription factor is only required very early during development in order to preserve the function of the axon over the lifetime of the worms.
 
This research provides fundamental insights into the cellular mechanisms needed to keep neuronal architecture, and therefore neuronal function, intact.  Furthermore, this has implications for neurodegenerative diseases, including Alzheimer's, Parkinson's, motor neurone, and Charcot-Marie-Tooth diseases, in which axonal degeneration is a common hallmark.

More information can be found on our publications page.
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Michelle confirmed as a PhD Candidate!

11/8/2017

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Congratulations to Michelle, who today successfully completed her 12 month PhD milestone requirements.  This involved writing a 6000 word literature review, a 2000 research report, and presenting a 20 minute seminar on her research.

Michelle is now officially confirmed as a PhD candidate!
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