Neumann Lab
  • Home
  • Our Research
    • Axonal Regeneration
    • Charcot-Marie-Tooth Disease and Mfn2
    • Axonal Degeneration
  • Our Team
    • Dr Brent Neumann
    • Jean-Sebastien Teoh
    • Tarika Vijayaraghavan
    • Samiksha Dhananjay
  • Publications
  • News/Blog
  • Image gallery
  • Contact
  • Links

Paper accepted at Cell Reports!!

16/8/2017

0 Comments

 
Update August 25th.
Our paper has now been officially accepted in Cell Reports!!

​
Brent has co-authored a paper that has been accepted in principle for publication in Cell Reports!

Our results define how the lin-14 heterochronic gene (one responsible for controlling the timing of developmental processes) controls axonal degeneration in C. elegans.  We found that interactions between an axon and it's surrounding environment is critical for preserving axonal structure throughout life.  Interestingly, the function of the LIN-14 transcription factor is only required very early during development in order to preserve the function of the axon over the lifetime of the worms.
 
This research provides fundamental insights into the cellular mechanisms needed to keep neuronal architecture, and therefore neuronal function, intact.  Furthermore, this has implications for neurodegenerative diseases, including Alzheimer's, Parkinson's, motor neurone, and Charcot-Marie-Tooth diseases, in which axonal degeneration is a common hallmark.

More information can be found on our publications page.
0 Comments



Leave a Reply.

    Categories

    All
    Awards
    Blog
    Events
    News
    Publication Info
    Trophy

    Picture

    Archives

    April 2020
    November 2019
    October 2019
    July 2019
    April 2019
    March 2019
    January 2019
    December 2018
    November 2018
    October 2018
    September 2018
    August 2018
    July 2018
    June 2018
    May 2018
    April 2018
    February 2018
    December 2017
    November 2017
    October 2017
    September 2017
    August 2017
    July 2017
    June 2017
    May 2017
    April 2017
    March 2017
    February 2017
    January 2017
    December 2016
    November 2016
    October 2016
    August 2016
    June 2016
    May 2016
    April 2016
    March 2016
    February 2016
    January 2016
    December 2015
    November 2015
    October 2015
    September 2015

    RSS Feed

Our Research

Axonal Regeneration
Charcot-Marie-Tooth Disease & Mfn2
Axonal Degeneration

Our Team

Lab members
Contact
Publications

Lab News

​Latest news.........
Paper published in PNAS Nexus!!
Follow @neumannlab
Biomedicine Discovery Institute
© COPYRIGHT 2015. ​ALL RIGHTS RESERVED.