Seb is now officially confirmed as a PhD candidate!
Congratulations to Seb, who successfully completed his 12 month PhD milestone requirements! This involved writing a 6000 word literature review, a 2000 research report, and presenting a 20 minute seminar on his research.
Seb is now officially confirmed as a PhD candidate!
Today the Neumann lab has had three separate manuscripts published by the Micropublication: biology journal!!
This is a wonderful new format of journal which publishes small snippets of data. We have published three articles related to our recent PNAS paper (Abay et al. 2017). This data was required for the review process, but was not included in the final published article. We have used the Micropublication format to have this data, which would never have been published elsewhere, now publicly available.
In our PNAS paper, we found that the level of regenerative axonal fusion is increased with advancing age. Here, we investigated whether daf-2, a gene with a central role in mediating lifespan, was responsible for this modulation of axonal fusion. Our data demonstrates that daf-2 is not specifically involved in modulating the level of axonal fusion over age, but instead is required for axonal regeneration in general at specific ages.
See our publications page here for links to the articles.
See here for more information on the Micropublication: biology journal.
The second Neumann/Pocock lab retreat is from Nov 30th - Dec 1st at Fairhaven/Airey's Inlet, near the beach on the Great Ocean Road in Victoria.
This is a great team bonding event, full of great food, swimming, cricket/soccer on the beach, games, and some work activities. This year our work activities involved groups of two presenting topics related to Equality and Diversity, Work/Life Balance, Managing Conflicts, Dealing With Stress, and Non-verbal communication.
Check out the pics here in our photo gallery.
Brent has accepted an invitation to become an ASMR Director from Nov 13th, 2017.
The Australian Society for Medical Research (ASMR) is Australia's peak body representing medical researchers in Australia. It has vital roles in advocating science to government, supporting early and mid career researchers, and bringing the importance of science to society at large. More information of the ASMR can be found here.
Brent will lead the professional development portfolio. Through this, ASMR aims to educate and inform early and mid career researchers by way of workshops and mentoring opportunities. Brent is keen to expand the program to make it a nationally recognised platform that provides crucial information for those in the sector.
This is a tremendous honour and Brent is very excited to begin this role.
The first paper from the Neumann lab has now been published by PNAS!!
Post from 22/08/17
The first publication from the Neumann lab has been accepted in PNAS!
This research was focused on regeneration of the nervous system, and on a highly efficient mechanism of repair known as axonal fusion. Axonal fusion allows regrowing axons to reconnect and fuse with their own separated fragments - in effect simply bridging the gap across the site of damage.
We found that axonal fusion restores full function to damaged neurons, allowing C. elegans to completely regain lost function within 48 hours. In addition, we found that injury results in changes to the axonal membrane, leading to the exposure of lipid ‘save-me’ signals. These 'save-me' signals mediate the level of axonal fusion, and are essential for the process to occur.
This research has implications for nervous system repair following injury to either the peripheral (limbs) or central nervous system (eg spinal cord injury).
In addition to be the first publication from our lab, this is the first publication for Zehra, Michelle and Sebastien!!
This is a wonderful achievement by the lab and well worth celebrating!
More info can be found on our publications page.
Nethmi has won a prize for her poster presentation at the Australian C. elegans Symposium!!
Her presentation was awarded an Honourable Mention - one of only four prize winners at the conference!
Congratulation Nethmi! A very well deserved prize and a great outcome from your first ever conference.
The whole Neumann lab is attending the Australian C. elegans Symposium (ACeS) held at the Queensland Brain Institute, The University of Queensland.
We are presenting our research across three talk (Joe, Seb, Michelle), and three posters (Ming, Simran, Nethmi), and Simran will be chairing a session.
A wonderful opportunity to bring the Australian C. elegans community together to meet and share our science!
The conference website is here and official hashtag is #ausWorms
Our review on Mitofusin-2 has now been published in Biological Reviews!! It was published on the journals 'early view' section on Oct 25th.
Post from 22/09/2017:
Our review article has been accepted by Biological Reviews!!
Titled "Structure, Function, and Regulation of Mitofusin-2 in Health and Disease", this is a comprehensive review of our current knowledge of the mitochondrial fusion protein Mitofusin-2. We wrote this in collaboration with Michael Lazarou.
This caps off an incredible couple of weeks for the Neumann lab, with this adding to publications accepted in PNAS and Cell Reports late last month.
Congratulations Simran, the lead author on our review!
The highly prestigious Neumann Lab trophy is awarded to a member of the lab who has achieved great success or for any other reason we deem appropriate!
The inaugural recipient was Valerie for getting strain number 100 - a wonderfully random achievement!
Current holder of the Top Achievement Award:
Ming: Magnificent Muscles!
Awarded for taking a truly beautiful image of the C. elegans body wall muscles (now on our CMT research page - see here)
7. Ming: Magnificent Muscles - taking a truly beautiful image of the C. elegans body wall muscles (now on our CMT research page - see here)
6. Michelle: Confirmed! - successfully completing her 12 month requirements as a PhD candidate
5. Tarika: Money Bags - being awarded three seperate scholarships on a single day
4. Michelle: WGS Success - successful sequencing and mapping various mutants isolated from genetic screening
3. Grace: First lab thesis - the first thesis completed in the Neumann Lab
2. Joe: CRISPR King - successfully getting a CRISPR mutant for the first time in the lab
1. Valerie: Strain 100 - generating strain #100 in the Neumann Lab
Brent is attending the Students of Brain Research (SoBR) symposium today at the Melbourne Brain Centre. He is serving as an invited judge for the poster sessions.
More information on the symposium and SoBR can be found here.